Fifth, our panellists can be regarded as experts in the field of assessment of the work ability of employees on long-term sick leave due to their specific and extensive expertise on this topic. Implications for clinical

practice and Adavosertib future research The results of this study suggest that after 2 years of sick leave, the focus of physicians should shift from a strictly disease-oriented approach to an individual and context-oriented approach to identify the factors that hinder recovery and encourage work resumption. Extending their focus to non-medical factors could enable physicians to target specific obstacles to work resumption and to adapt their advice to help sick workers to remain at work or to

get back to work more quickly after a period of illness. The identification by health INCB024360 datasheet IWR-1 in vitro professionals of factors that hinder or promote RTW at an earlier stage of sick leave, preferably not later than the first 3 months of sick leave, and the implementation of strategies and interventions targeting these factors could help decrease the chance of developing chronic work disability. Although we gained valuable insight into factors that are relevant for RTW that should be addressed by the assessment of work ability of long-term sick-listed employees, future studies should determine whether these factors occur frequently and whether they affect RTW outcomes. The results represent the consensus of experts in this field and will be used to design a tool to support the medical assessment of the work ability of employees on long-term sick leave. We expect that the results of the present study will improve the overall quality of the assessment of the work ability and subsequent guidance of sick-listed employees by emphasising the importance SPTLC1 of taking into account non-medical factors. The relation between thoughts and RTW is an important finding, as some factors related to thoughts and beliefs are potentially amenable

to change, which offers possibilities for the improvement of work participation of employees on long-term sick leave. These findings suggest that the employees’ thoughts and behaviour regarding RTW may be at least as important as the medical condition of the sick-listed employee, especially in chronic conditions. Acknowledging and addressing factors such as lack of motivation, negative attitude towards RTW, negative illness perceptions and secondary gain issues is required to assess work ability accurately. Early RTW interventions targeting thoughts and behaviour at earlier stages of sick leave, preferably not later than after 3 months of sick leave, could also be beneficial for employees on long-term sick leave due to other types of complaints.