As shown in Figure 2, by in case of films containing 2 wt% chitosan, the WVP Anticancer Compound Library solubility dmso was effectively reduced (R2 = 0.99) by increasing the nanoclay content up to 3 wt% in the polymer

matrix. In addition, nanocomposite films containing 2 wt% chitosan resulted in the highest tensile strength of 1.78 kgf/mm2. Those results agree well with previous literature, whereas biofilms with high tensile strength had lower WVP values [17]. Encapsulation of compounds protects a sensitive substance within the capsule, physically isolating it from the external environment. This barrier can provide protection against various agents, such as oxygen, water, and light, allows for a controlled release of the substance, and prevents contact with other components in a mixture 18, 19 and 20•. Nanotechnology in foods is new as

compared to the biomedical area and information technology industries, where nanotechnology has been used in the manufacture of materials [21]. Nanocapsules are composed of an active central core surrounded by a thin polymeric wall, providing Rapamycin purchase protection of the active compound against oxygen, water and/or light, allowing for a controlled release of the substance and/or preventing contact with other components in a mixture 22 and 23. Bioactive peptides are protein fragments which have a positive impact on the functions and conditions of living beings [24]. According to Harnedy and Fitzgerald [25] and Dewapriya and Kim [26], marine organisms are rich sources of structurally diverse bioactive nitrogenous components. The activities including antihypertensive, antioxidant, anti-microbial, anti-coagulant, anti-diabetic, anti-cancer, immunostimulatory, calcium-binding, hypocholesteremic and appetite suppression Grape seed extract have been reported [27]. Encapsulation may provide increased antimicrobial efficiency to peptides (Figure 3). The antilisterial peptide pediocin was encapsulated in

nanovesicles prepared from partially purified soybean phosphatidylcholine [28••]. According to Dewapriya and Kim [26], it is well established that bioactive proteins and protein hydrolysates are two of most common terms in modern nutritional supplements. However, all of the high protein sources cannot be used to develop supplements without considering their biological value which is the amount, or percentage of protein that the body is able to absorb [29]. Many studies have demonstrated that, when incorporated into edible films and coatings, antimicrobial agents can be effective in reducing levels of pathogenic organisms like Escherichia coli O157:H7, Listeria monocytogenes, Salmonella Typhi and Staphylococcus aureus 29 and 30.