DIHS-associated myocarditis was suspected and management with circulation assistance devices and steroid pulse therapy were started, resulting in satisfactory resolution. A rise in titer of human herpesvirus-6, cytomegalovirus and Herpes simplex virus-1 antibodies was detected. Although minocycline-induced myocarditis is rare, this severe drug reaction should be considered with DIHS.”
“Hypertension is the commonest medical condition
in Ireland.
(1) To examine the level of awareness of blood pressure (BP) in the population and (2) to ascertain the opinion of general practitioners (GPs) in diagnosis and management of hypertension.
BP measurements and assessment of BP awareness were performed in a sub-sample of the general population (n = 1,071). The opinion of GPs (n = 1,037) on hypertension was determined in a postal survey.
Amongst the population sampled (45 +/- A 13 years, mean age +/- Selleck MLN2238 A SD), almost half had elevated BP (> 140/90 mmHg) but
only half of those were already on antihypertensives. 40% had no knowledge of their BP and 54% were not aware selleck of what constituted normal BP. While some 80% of GPs said they followed British guidelines, their practice was more in keeping with the European guidelines. Approximately, 90% of GPs required ambulatory BP recording to confirm diagnosis of hypertension. First choice antihypertensive agents were ACE inhibitors and angiotensin receptor antagonists in younger patients and diuretics and ACE inhibitors in older patients.
These results suggest that there is a need for further public education on BP and nationally agreed hypertension guidelines.”
“This study investigated the status of contamination of organohalogen compounds (OCs) such as polychlorinated biphenyls find protocol (PCBs) and brominated flame retardant (BFRs), including polybrominated
diphenyl ethers (PBDEs) and hexabromocyclododecanes (HBCDs) in human milk samples from several locations in India. The levels of OCs were significantly higher in the milk of mothers living in and near municipal dumping site than other locations indicating that the open dumping sites for municipal wastes act as potential sources of these contaminants in India. The PCB concentrations observed in this study tended to decrease compared to those in the matched locations reported previously, probably due to the restriction of technical PCB usage in India. PBDE levels in human milk were two to three folds lower than those of PCBs in all the sampling locations investigated. Congener profiles of PCBs and PBDEs were different between samples from the dumping site mothers and general populations in other areas suggesting the presence of region-specific sources and pathways. HBCDs were detected in human milk from only two sites, with much lower concentrations and detection frequencies compared to PCBs and PBDEs.