Vet Rec 2005,156(6):186–187.PubMed 18. Cottell JL, Webber MA, Piddock LJ: Persistence of transferable ESBL resistance in the absence of Dorsomorphin in vivo antibiotic pressure. Antimicrob Agents Chemother 2012,56(9):4703–4706.PubMedCentralPubMedCrossRef 19. Thomason LC, Costantino N, Shaw DV, Court DL: Multicopy plasmid modification Doramapimod mouse with phage lambda Red recombineering. Plasmid 2007,58(2):148–158.PubMedCentralPubMedCrossRef 20. Nielsen AK, Gerdes K: Mechanism of post-segregational killing by hok -homologue pnd of plasmid R483: two translational control elements in the pnd mRNA. J Mol Biol 1995,249(2):270–282.PubMedCrossRef 21. Bradley DE: Characteristics and function

of thick and thin conjugative pili determined by transfer-derepressed plasmids of incompatibility groups I1, I2, I5, B, K and Z. J Gen Microbiol 1984,130(6):1489–1502.PubMed 22. Komano T, Kim SR, Yoshida T: Mating variation by DNA inversions of shufflon in plasmid R64. Adv Biophys 1995, 31:181–193.PubMedCrossRef 23. Sharan SK, Thomason LC, Kuznetsov SG, Court DL: Recombineering: a homologous recombination-based method of genetic engineering. Nat Protoc 2009,4(2):206–223.PubMedCentralPubMedCrossRef 24. Furuya PLX-4720 cost N, Komano T: Nucleotide sequence and characterization of the trbABC region of the IncI1 plasmid R64: existence of the pnd gene for plasmid maintenance within the transfer region. J Bacteriol 1996,178(6):1491–1497.PubMedCentralPubMed

25. Friedman SA, Austin SJ: The P1 plasmid-partition system synthesizes two essential proteins from an autoregulated operon. Plasmid 1988,19(2):103–112.PubMedCrossRef SPTLC1 26. Komano T, Yoshida T, Narahara K, Furuya N: The transfer region of IncI1 plasmid R64: similarities between R64 tra and Legionella icm/dot genes. Mol Microbiol 2000,35(6):1348–1359.PubMedCrossRef 27. Yoshida T, Kim SR, Komano T: Twelve pil genes are required for biogenesis of the R64 thin pilus. J Bacteriol 1999,181(7):2038–2043.PubMedCentralPubMed 28. Call DR, Singer RS, Meng D, Broschat

SL, Orfe LH, Anderson JM, Herndon DR, Kappmeyer LS, Daniels JB, Besser TE: bla CMY-2-positive IncA/C plasmids from Escherichia coli and Salmonella enterica are a distinct component of a larger lineage of plasmids. Antimicrob Agents Chemother 2010,54(2):590–596.PubMedCentralPubMedCrossRef 29. Potron A, Poirel L, Nordmann P: Plasmid-mediated transfer of the bla NDM-1 gene in Gram-negative rods. FEMS Microbiol Lett 2011,324(2):111–116.PubMedCrossRef 30. Datsenko KA, Wanner BL: One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A 2000,97(12):6640–6645.PubMedCentralPubMedCrossRef 31. Hartskeerl R, Zuidweg E, van Geffen M, Hoekstra W: The IncI plasmids R144, R64 and ColIb belong to one exclusion group. J Gen Microbiol 1985,131(6):1305–1311.PubMed 32. Baugh S, Ekanayaka AS, Piddock LJ, Webber MA: Loss of or inhibition of all multidrug resistance efflux pumps of Salmonella enterica serovar Typhimurium results in impaired ability to form a biofilm.