We show that including

unsynchronized food-mediated migration would make the behaviour of a plankton model more realistic. This would imply a significant enhancement of ecosystem’s stability and some additional mechanisms of regulation of algal blooms. In the system with food-mediated unsynchronized vertical migration, the control of phytoplankton by herbivorous becomes possible even for very large concentrations of nutrients in the water (formally, when the system’s carrying capacity tends to infinity). (C) 2009 Elsevier Ltd. All rights reserved.”
“Adult rats were used to identify the effects of infrasound on neurogenesis in the hippocampal dentate gyrus. After 7 consecutive days’ exposure to infrasound of see more 16 Hz at 130 dB, immunostaining of 5-bromo-2′-deoxyuridine (BrdU) and doublecortin (DCX) was preformed. Compared with those in normal groups, the numbers of BrdU(+) and DCX(+)/BrdU(+) cells in the subgranular zone in infrasound groups were significantly decreased at 3, 6, 10 and 14 days and returned to normal at 18 days. The percentage of BrdU(+) cells that were co-labeled with DCX showed no significant differences between the infrasound and normal groups. These data suggest that infrasound inhibits the cell proliferation in adult rat dentate gyrus but has no effects on early migration and differentiation

of these newborn cells. NeuroReport 21:585-589 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.”
“Regulation selleck compound of mRNA translation has been held responsible Idoxuridine for effects of diet, age, alcohol, hormones, hibernation, disease

and hypoxia on protein synthesis in animal tissues. Dietary effects are due to concentrations of amino acids and insulin in circulation that affect activities of two key translational regulators, eukaryotic initiation factor 2 (172) and eukaryotic initiation factor 4E binding protein I (Bp). To construct a platform for prediction of global protein synthesis to nutritional stimuli, a dynamic, mechanistic model of translational control in whole tissues was developed. The model was composed of a set of differential equations which describe the dynamics of I I state variables: tRNA and acyl-tRNA for leucine (Leu), limiting (Laa) and other amino acids (Oaa), inactivated F2 with GDP (F2d), activated F2 with GTP (F2t), F4e, Bp and its complex with F4e (4eBp), available rnRNA start codons (AUG), and active ribosomes (Arib). Material was assumed to flow from one variable to another according to mass-action kinetics or Michaelis-Menten form. Uncharged tRNA inhibit GTP exchange on eIF2, and free amino acids and insulin inhibit reversible sequestration of F4e by Bp. Initial conditions and parameters were set for a skeletal muscle fractional synthesis rate of 10%/d and ribosome transit time of 80 s.