When tumor recurrence was evaluated in 31 patients who underwent TBF-based partial hepatectomy, only three cases (9.7%) developed recurrences in the same segment, indicating that most recurrences due to systemic IM or MC could not be prevented if anatomical segmentectomy was performed (Fig. 7). In addition, no local, cutting-edge (<1 cm) recurrences were observed in these patients. A recent study revealed that the impact of TBF-based hepatectomy on survival is comparable to that of anatomical hepatectomy.[15] These findings are very convincing because the high-risk area of local IM was completely resected by this type of surgery. Therefore, compared Obeticholic Acid cost with anatomical hepatectomy, TBF-based hepatectomy

for HCC is less invasive and enables us to preserve more liver function with comparable curability. Because locoregional treatment click here cannot prevent hepatic recurrences by systemic IM or MC, these need to be treated with systemic chemotherapy. The occurrence of MC after surgery may also be suppressed by treating the underlying chronic hepatitis. TUMOR BLOOD FLOW-BASED hepatectomy

for HCC is basically identical to anatomical hepatectomy in terms of the concept that tumor spreads through the portal blood flow where tumor blood flows in. The difference is whether or not the confirmation of TBF area as safety margin is done before surgery. TBF-based hepatectomy is minimally invasive but as sufficiently curative as anatomical hepatectomy because the high-risk

area of local IM is identified and completely resected. “
“Background And Aims:  The aims of the present study were to evaluate the role of moderate-to-severe endoscopic gastric atrophy (EGA) on predicting Operative Link on Gastritis Assessment (OLGA) gastritis stage, and to assess the association of high-stage OLGA gastritis with gastric neoplasia in patients with non-ulcer dyspepsia. Methods:  A cross-sectional study was carried out on 280 dyspeptic outpatients. EGA was assessed according to the Kimura–Takemoto classification. Gastritis stage was established according to Phosphatidylinositol diacylglycerol-lyase the OLGA staging system and gastric neoplasia was assessed according to the Vienna classification. The pathologists who read the specimens were kept blind to the endoscopic results. Results:  The mean age of patients was 46.1 years (range 20–78 years) with a male-to-female ratio of 1:1. High-stage gastritis (e.g. stage III or IV) was confirmed in 13 (4.6%) patients. All of these patients were more than 40 years-of-age (P = 0.01), had Helicobacter pylori infection (P = 0.0006) and moderate-to-severe EGA (P < 0.001). Low-grade dysplasia was found in seven patients: 4/13 (30.7%) with high-stage gastritis versus 3/267 (1.1%) with low-stage gastritis (P < 0.001). Six of these patients had moderate-to-severe EGA (P = 0.048). The sensitivity, specificity, positive predictive value and negative predictive value of this endoscopic finding in high-stage gastritis diagnosis were 100%, 57.