The patient��s medical history was significant for an electrical

The patient��s medical history was significant for an electrical injury suffered 3 years earlier, after Palbociclib cell cycle which he began to notice the visual decline. The injury Inhibitors,Modulators,Libraries occurred when he was grasping the extended cables of a crane and the boom came into contact with high-tension transmission lines carrying a reported 115,000 Volt potential. He underwent amputation of all four extremities and remained in the burn unit for three months, receiving treatment for deep tissue burns on his left side, covering roughly 40% of the torso. On ophthalmological examination, visual acuity was 20/20 in the right eye and 20/40-2 in the left eye, with no improvement on pinhole. The anterior examination of the left eye revealed a posterior subcapsular cataract with trace nuclear sclerotic changes (Figure 1A) The optic nerve was sharp, pink, and full, with a cup/disc ratio of 0.

4 and an early posterior vitreous detachment. On dilated fundus examination of the left eye, preretinal fibrosis and chorioretinal atrophy surrounding the optic nerve and two smaller regions superonasal and inferotemporal of the same description were Inhibitors,Modulators,Libraries observed. (Figure 1B) Results of optical coherence tomography (OCT) correlated with fundus examination findings, showing retinal thinning and retinal pigment epithelium/choriocapillary irregularity in the area adjacent to the optic nerve ( Figure 2). Anterior and posterior examination of right eye demonstrated normal anatomical findings, as did the OCT that was performed ( Figure 3). Figure 1 Left eye of electrical trauma patient.

A, Fundus photograph of left eye showing fibroses and atrophy of the retina surrounding the optic disc. B, Cataract of the lens. Figure 2 A, OCT of the left retina showing Inhibitors,Modulators,Libraries atrophy of the retina as well as the extent of the changes relative to the fovea. B, fundus photograph Inhibitors,Modulators,Libraries showing position of scan. Figure 3 Normal anatomy of the right eye. A, posterior pole. B, OCT scan of retina. C, fundus photograph showing position of scan. Based on our examination we concluded that the macula was of sufficient viability that cataract extraction would likely result in an improvement in vision. Cataract extraction was subsequently performed and an intraocular lens was implanted. Postoperatively his visual acuity improved to 20/30.

Discussion The ocular complications resulting from electrical injuries are quite varied; chemosis, corneal perforation, iritis, cataract, retinal pigment epithelium damage, macular Inhibitors,Modulators,Libraries edema, retinal detachment, macular hole, optic neuritis, and choroidal atrophy have all been previously reported.4 The development of cataracts Batimastat has been postulated to be induced by direct effect on the proteins of the lens from the current or by contraction of the ciliary muscle causing a concussion-type injury, changes in capsular permeability, or thermal damage.

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